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Molecular and Enviro Toxicology
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Molecular and Environmental Toxicology Center

Molecular and Environmental Toxicology at the University of Wisconsin–Madison focuses on biochemistry, carcinogenesis, cell biology, developmental biology, genetics, genomics, immunology, neurobiology, proteomics, and xenobiotic fate and metabolism research in a collaborative, interdisciplinary community of high-caliber students, faculty members, and facilities.

Molecular and Environmental Toxicology Center
1300 University Avenue
1530 MSC
Madison, WI 53706
Fax 262-5245

Training Grant News
  • Tracie Baker, DVM, has received a five-year NIH K01 grant entitled "Adult and Transgenerational Toxicity Due to Developmental TCDD Exposure". She also received the 2013 Young Investigator Award from the Midwest Regional Chapter - SOT. Tracie works with Warren Heideman and Dick Peterson and is also working on her PhD with the METC program.
  • Taryn James, PhD, has received a postdoctoral fellowship from the PhRMA association, entitled "Mechanisms and Molecular Targets of Phytoestrogens in Breast Cancer In Vivo". Taryn works with Wei Xu.
  • Adam Mastrocola, PhD, has received an American Cancer Society postdoctoral fellowship entitled "Defining the Roles of Fused in Sarcoma Protein in the DNA Damage Response". Adam works with Randy Tibbetts.
  • Ashleigh Theberge, PhD, received two awards at the 2013 Society of Toxicology annual meeting: "First Place Winner of the In Vitro and Alternative Methods Specialty Section Student Award in the Postdoctoral Scholar category" and "In Vitro and Alternative Methods Specialty Section MB Research Award for Distinction in Practical In Vitro and Alternative Toxicology Methods". Ashleigh works with David Beebe and Wade Bushman.

  • 2013
    • Emmanuel Vazquez-Rivera has received two honors: a predoctoral fellowship from the National Science Foundation and a Young Investigator Award from the American Society for Microbiology. Emmanuel works with Tim Bugni.
    • Ashley Brinkman received the 2013 Student Achievement Award presented by the Women in Toxicology Special Interest Group. Ashley works with Wei Xu.

    • Amy Irving
      received a Peer Mentoring Award from UW-Madison. Amy works with Bill Dove.

    Our Faculty In The News
    Vincent Cryns, MD, UW doctors make breakthrough in breast cancer research - Scientists found protein that cancer cells use to spread to brain Article

    Colin Jefcoate, PhD, Helmut Beinert Professor of Biochemistry, was appointed to a WARF named chair for research on identifying molecular mechanisms exploited by toxic agents such as dioxin to disrupt cellular signaling conducted by hormones and other proteins.

    Bill Dove, PhD, received the 2013 Emeritus Faculty Award in Basic Sciences by the Wisconsin Medical Alumni Association. This award is given to a basic scientist who demonstrated long and effective service to the UW School of Medicine and Public Health in teaching and/or research or noteworthy administration, including program development. Article

    Wei Xu, PhD, received the 2013 Society of Toxicology Achievement Award. This award is presented to a member of the Society of Toxicology who has made significant contributions to toxicology. Article

    Emery Bresnick, professor of cell and regenerative biology, earned a Kellett award, supported by the Wisconsin Alumni Research Foundation - Article

    Patricia Keely, professor of cell and regenerative biology at the UW School of Medicine and Public Health, earned a Romnes award, which recognizes exceptional faculty members who have earned tenure within the last four years. - Article

    2013-January - Allen-Hoffmann
    Burn patients avoid painful surgery in trial of skin substitute

    "This is the first skin substitute to ever achieve this level of efficacy, potency and consistency in severe burns," Lynn Allen-Hoffman, CEO and chief scientific officer, said in a statement. - Article

    2012-Oct - Pedersen
    Center gets small to study nanoparticles in environment - "A lot of studies have been conducted with whole organisms examining rather severe effects — like death — that only appear at high concentrations," says Joel Pedersen, an environmental chemistry professor in UW-Madison's Soil Science Department. "Some of the more subtle effects are only beginning to be examined." - Article

    2012-March - Bradfield
    Twleve outstanding faculty members at UW-Madison have been named winners of this year's Kellett Mid-Career Awards. Included was METC Director Chris Bradfield. His research team has identified the cellular receptor for the pollutant dioxin and has helped defined the molecular clock that governs circadian behavior and physiology. Article

    2011-October - Allen Hoffmann
    $4.6 million grant will help Stratatech start clinical trials of skin substitute
    Read more: Wisconsin State Journal

    2011-October - Karasov
    UW-Madison to collaborate on new federal Climate Science Center

    The University of Wisconsin-Madison is among several institutions that will collaborate through a new federal Northeast Climate Science Center to study the effects of climate change on ecosystems, wildlife, water and other resources. Article

    2011-May - Bresnick
    Dr. Emery Bresnick, professor of cell and regenerative biology and member of the University of Wisconsin Carbone Cancer Center at the School of Medicine and Public Health (SMPH), has been given a coveted MERIT Award by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a division of the National Institutes of Health (NIH). Article

    2011-May - Xing
    Two Wisconsin researchers, including a University of Wisconsin-Madison oncologist, have been named Shaw Scientists by the Greater Milwaukee Foundation. Article

    2011-March - Lingjun
    Awardees' expertise nclude psychology, art, physics, genetics
    The Romnes awards recognize exceptional faculty members who have earned tenure within the last four years. Winners receive unrestricted $50,000 award for researcg. Article

    2011-March - Klein
    Four professors honored with Hilldale Awards
    The top honor for faculty members who have excelled in teaching, research, and service in areas of biological sciences, physical sciences, social studies and arts and humanities. Article

    2011-March - Huttenlocher
    One of Eleven awarded Kellett Mid-Career Award
    - The Kellett award, supported by WARF recognizes outstanding mid-career faculty members who hare five to twenty years past the first promotion to a tenured posiiton. Each winner receives $60,000 flexible research award. Article

    2011-January - Lingjun
    Awarded H.I. Romnes Faculty Fellowship
    This unrestricted 5-year research award recognizes the University's most outstanding recently tenured faculty. Article
    METC promotes research at UW-Madison and the UW System that addresses fundamental mechanisms through which toxicants produce adverse effects; provides ways to assess or predict the impact of these agents on humans and other species; develops biological and physicochemical processes that can control releases or deplete the environment of these harmful agents. Programs of the METC are supported in part by grants T32 ES07015 and T35 ES07295 from the National Institute of Environmental Health Sciences.
Calendar Of Events
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Application deadline for Fall 2015 admission consideration is December 1st

Application deadline for Summer 2015 Intergrated Biological Sciences Summer Research Program (IBS-SRP) is February 15, 2015.

Current issue of the Environmental Factor is now online

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Journal Covers

September 2012 - Yongna Xing, PhD
Identification of the Ah-Receptor Structural Determinants for Ligand Preferences

January 2011 - Erin Shanle and Wei Xu, PhD
Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action.

Dec 2009 - Chris Bradfield, PhD
D-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor and Structural Identification of Diindole Agonists of the Aryl Hydrocarbon Receptor

September 2009 - Travis Jerde, PhD and Wade Bushman, MD, PhD
IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasia
Date Last Updated: 11/25/2014 webteam@med.wisc.edu