Molecular and Environmental Toxicology Center
Molecular and Environmental Toxicology at the University of Wisconsin–Madison focuses on biochemistry, carcinogenesis, cell biology, developmental biology, genetics, genomics, immunology, neurobiology, proteomics, and xenobiotic fate and metabolism research in a collaborative, interdisciplinary community of high-caliber students, faculty members, and facilities.
Molecular and Environmental Toxicology Center
1300 University Avenue
Madison, WI 53706
Training Grant News, has received a five-year NIH K01 grant entitled "Adult and Transgenerational Toxicity Due to Developmental TCDD Exposure". She also received the 2013 Young Investigator Award from the Midwest Regional Chapter - SOT. Tracie works with Warren Heideman and Dick Peterson and is also working on her PhD with the METC program. Taryn James, PhD, has received a postdoctoral fellowship from the PhRMA association, entitled "Mechanisms and Molecular Targets of Phytoestrogens in Breast Cancer In Vivo". Taryn works with Wei Xu.Adam Mastrocola, PhD, has received an American Cancer Society postdoctoral fellowship entitled "Defining the Roles of Fused in Sarcoma Protein in the DNA Damage Response". Adam works with Randy Tibbetts. Ashleigh Theberge, PhD, received two awards at the 2013 Society of Toxicology annual meeting: "First Place Winner of the In Vitro and Alternative Methods Specialty Section Student Award in the Postdoctoral Scholar category" and "In Vitro and Alternative Methods Specialty Section MB Research Award for Distinction in Practical In Vitro and Alternative Toxicology Methods". Ashleigh works with David Beebe and Wade Bushman.
2013 has received two honors: a predoctoral fellowship from the National Science Foundation and a Young Investigator Award from the American Society for Microbiology. Emmanuel works with Tim Bugni. Ashley Brinkman received the 2013 Student Achievement Award presented by the Women in Toxicology Special Interest Group. Ashley works with Wei Xu.
Amy Irving received a Peer Mentoring Award from UW-Madison. Amy works with Bill Dove.
Our Faculty In The News
Vincent Cryns, MD, UW doctors make breakthrough in breast cancer research - Scientists found protein that cancer cells use to spread to brain Article
Colin Jefcoate, PhD, Helmut Beinert Professor of Biochemistry, was appointed to a WARF named chair for research on identifying molecular mechanisms exploited by toxic agents such as dioxin to disrupt cellular signaling conducted by hormones and other proteins.
Bill Dove, PhD, received the 2013 Emeritus Faculty Award in Basic Sciences by the Wisconsin Medical Alumni Association. This award is given to a basic scientist who demonstrated long and effective service to the UW School of Medicine and Public Health in teaching and/or research or noteworthy administration, including program development. Article
Wei Xu, PhD, received the 2013 Society of Toxicology Achievement Award. This award is presented to a member of the Society of Toxicology who has made significant contributions to toxicology. Article
Emery Bresnick, professor of cell and regenerative biology, earned a Kellett award, supported by the Wisconsin Alumni Research Foundation - Article
Patricia Keely, professor of cell and regenerative biology at the UW School of Medicine and Public Health, earned a Romnes award, which recognizes exceptional faculty members who have earned tenure within the last four years. - Article
2013-January - Allen-Hoffmann
Burn patients avoid painful surgery in trial of skin substitute
"This is the first skin substitute to ever achieve this level of efficacy, potency and consistency in severe burns," Lynn Allen-Hoffman, CEO and chief scientific officer, said in a statement. - Article
2012-Oct - Pedersen
Center gets small to study nanoparticles in environment - "A lot of studies have been conducted with whole organisms examining rather severe effects — like death — that only appear at high concentrations," says Joel Pedersen, an environmental chemistry professor in UW-Madison's Soil Science Department. "Some of the more subtle effects are only beginning to be examined." - Article
2012-March - Bradfield
Twleve outstanding faculty members at UW-Madison have been named winners of this year's Kellett Mid-Career Awards. Included was METC Director Chris Bradfield. His research team has identified the cellular receptor for the pollutant dioxin and has helped defined the molecular clock that governs circadian behavior and physiology. Article
2011-October - Allen Hoffmann
$4.6 million grant will help Stratatech start clinical trials of skin substitute
Read more: Wisconsin State Journal
2011-October - Karasov
UW-Madison to collaborate on new federal Climate Science Center
The University of Wisconsin-Madison is among several institutions that will collaborate through a new federal Northeast Climate Science Center to study the effects of climate change on ecosystems, wildlife, water and other resources. Article
2011-May - Bresnick
Dr. Emery Bresnick, professor of cell and regenerative biology and member of the University of Wisconsin Carbone Cancer Center at the School of Medicine and Public Health (SMPH), has been given a coveted MERIT Award by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a division of the National Institutes of Health (NIH). Article
2011-May - Xing
Two Wisconsin researchers, including a University of Wisconsin-Madison oncologist, have been named Shaw Scientists by the Greater Milwaukee Foundation. Article
2011-March - Lingjun
Awardees' expertise nclude psychology, art, physics, genetics The Romnes awards recognize exceptional faculty members who have earned tenure within the last four years. Winners receive unrestricted $50,000 award for researcg. Article
2011-March - Klein
Four professors honored with Hilldale Awards The top honor for faculty members who have excelled in teaching, research, and service in areas of biological sciences, physical sciences, social studies and arts and humanities. Article
2011-March - Huttenlocher
One of Eleven awarded Kellett Mid-Career Award - The Kellett award, supported by WARF recognizes outstanding mid-career faculty members who hare five to twenty years past the first promotion to a tenured posiiton. Each winner receives $60,000 flexible research award. Article
2011-January - Lingjun
Awarded H.I. Romnes Faculty Fellowship This unrestricted 5-year research award recognizes the University's most outstanding recently tenured faculty. Article
METC promotes research at UW-Madison and the UW System that addresses fundamental mechanisms through which toxicants produce adverse effects; provides ways to assess or predict the impact of these agents on humans and other species; develops biological and physicochemical processes that can control releases or deplete the environment of these harmful agents. Programs of the METC are supported in part by grants T32 ES07015 and T35 ES07295 from the National Institute of Environmental Health Sciences.
|Calendar Of Events
Application deadline for Fall 2015 admission consideration is December 1st
Application deadline for Summer 2015 Intergrated Biological Sciences Summer Research Program (IBS-SRP) is February 15, 2015.
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September 2012 - Yongna Xing, PhD
Identification of the Ah-Receptor Structural Determinants for Ligand Preferences
January 2011 - Erin Shanle and Wei Xu, PhD
Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action.
Dec 2009 - Chris Bradfield, PhD
D-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor and Structural Identification of Diindole Agonists of the Aryl Hydrocarbon Receptor
September 2009 - Travis Jerde, PhD and Wade Bushman, MD, PhD
IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasia