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Klein, Bruce S

Bruce S. Klein, MD - Email
Professor


Research Interest
Molecular medical mycology -- cellular and molecular basis of immunity to medical fungi; genetics of virulence; molecular mechanisms of pathogenesis

Home Dept - Medical Microbiology & Immunology; School of Medicine and Public Health
Affiliated Depts - Molecular and Environmental Toxicology; Pediatrics; and Internal Medicine

Address
4303 Microbial Sciences Building
1550 Linden Drive
Madison, WI 53706

Milestones
2008 WARF Named Professor
2008 SPAR Senior Investigator Award
2005 NIH MERIT R37

Research


Publications
  • Klein BS, Tebbets B. Dimorphism and virulence in fungi. Curr Opin Microbiol. 2007 Aug;10(4):314-9. Review.
  • Nemecek JC, Wüthrich M, Klein BS. Detection and measurement of two-component systems that control dimorphism and virulence in fungi. Methods Enzymol. 2007;422:465-87.
  • Krajaejun T, Gauthier GM, Rappleye CA, Sullivan TD, Klein BS. Development and application of a green fluorescent protein sentinel system for identification of RNA interference in Blastomyces dermatitidis illuminates the role of septin in morphogenesis and sporulation. Eukaryot Cell. 2007 Aug;6(8):1299-309.
  • Gauthier GM, Safdar N, Klein BS, Andes DR. Blastomycosis in solid organ transplant recipients.
    Transpl Infect Dis. 2007 Dec;9(4):310-7
  • Cutler JE, Deepe GS Jr, Klein BS. Advances in combating fungal diseases: vaccines on the threshold. Nat Rev Microbiol. 2007 Jan;5(1):13-28. Review
  • Wüthrich M, Filutowicz HI, Allen HL, Deepe GS, Klein BS.
    V beta1+ J beta1.1+/V alpha2+ J alpha49+ CD4+ T cells mediate resistance against infection with Blastomyces dermatitidis. Infect Immun. 2007 Jan;75(1):193-200
  • Wüthrich M, Finkel-Jimenez B, Brandhorst TT, Filutowicz HI, Warner T, Klein BS. Analysis of non-adhesive pathogenic mechanisms of BAD1 on Blastomyces dermatitidis. Med Mycol. 2006 Feb;44(1):41-9
  • Nemecek JC, Wüthrich M, Klein BS. Global control of dimorphism and virulence in fungi. Science. 2006 Apr 28;312(5773):583-8
Check PubMed for other publications by Bruce S. Klein


Date Last Updated: 04/09/2009 webteam@med.wisc.edu