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Blanke, Kristina
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Boley, Patricia
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Bolterstein, Elyse
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Booth, Clarissa
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Brody, Matthew
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Bultman, JoAnna
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Burns, Felipe
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Desotelle, Josh
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Ding, Lina
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Elmergreen, Tammy
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Hutchinson, John
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Irving, Amy
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Irving, Roy
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Johnson, Brian
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Johnson, Delinda
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Johnson, Shaina
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Jung-Hynes, Brittney
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Kumar, Kartik
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Lee, Sung-Kyoung
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Lorch, Jeff
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Mehta, Vatsal
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Novick, Rachel
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Park, Heesoo
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Pham, Ly
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Poenitzsch, Ashley
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Rhoads, Keelia
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Rufer, Echoleah
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Sand, Jordan
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Schmit, Travis
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Shan, Weihua
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Shanle, Erin
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Shetty, Ameesha
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Syed, Deeba
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Tarapore, Rohinton
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Velasco, Javier
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Wiecinski, Paige
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Wong, Letitia
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Yang, Sarah
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Yu, Min
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Zhao, Yun
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Calkins, Marcus
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Mehta, Vatsal
 Vatsal Mehta -Email
PhD Candidate - Started 2003
Mumbai, India
Lab of Warren Heideman, PhD
Graduate Work
Master of Science, Animal Physiology (2002)
Wilson College, University of Mumbai
Undergraduate Work
Bachelor of Science, Zoology (2000)
Bachelor of Science, Biochemistry (2000)
St. Xavier's College, University of Mumbai
Memberships
Society of Toxicology (2005)
Interests/Hobbies
Playing squash, biking, and fishing
Research as of August 2008
Zebrafish have the unique ability to regenerate injured spinal cord, retina, fins and more recently the heart. Humans and other vertebrate species lack the ability to regenerate damaged cardiac tissue and instead undergo myocardial hypertrophy and display scar formation. This makes the zebrafish an excellent model to understand the molecular mechanisms by which heart regeneration occurs. Environmental contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) have been found to inhibit the normal healing process in zebrafish by activating the aryl hydrocarbon receptor pathway. Changes in cell proliferation, epicardial cell activation and myocardial differentiation are currently being investigated to understand this process.
Publications - Mehta V, Peterson RE, Heideman W. - 2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure prevents cardiac valve formation in developing zebrafish. Toxicol Sci. 2008 Aug;104(2):303-11.
- Prasch AL, Tanguay RL, Mehta V, Heideman W, Peterson RE. (2006) Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1.Mol Pharmacol. Mar;69(3):776-87.
- Ghorpade N, Mehta V, Khare M, Sinkar P, Krishnan S, Rao CV.(2002). Toxicity study of diethyl phthalate on freshwater fish Cirrhina mrigala. Ecotoxicol Environ Saf. Oct;53(2):255-8.
 Posters- 2008 - 8th International Conference on Zebrafish Development and Genetics. Madison, WI. 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Inhibits Heart Regeneration in Adult Zebrafish Following Ventricular Resection - Mehta V, Peterson R.E. and Heideman W. Abstract #566.
- 2008 - Society of Toxicology 2008 Meeting-Seattle, WA. Adult Zebrafish Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Display Reduced Myocardial Regenerative Capacity Following Ventricular Resection - Mehta V., Peterson R.E. and Heideman W. The Toxicologist (a Supplement to Toxicological Sciences) 102 (1) Abstract #1658, p 341.
- 2007 - Society of Toxicology- Midwest Regional Chapter 2007 Meeting - Lincolnshire, IL 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Induces Heart Valve Defects in Embryonic Zebrafish - Mehta V., Peterson R.E. and Heideman W.
- 2007 - Society of Toxicology 2007 Meeting- Charlotte, NC. Embryonic Zebrafish Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exhibit Defects in Cardiac Valve Formation and Function - Mehta V., Peterson R.E. and Heideman W. The Toxicologist (a Supplement to Toxicological Sciences) 96 (1) Abstract #361, p 75.
- 2007 - Society Of Toxicology 2007 Meeting - Charlotte, NC. Effect of TCDD on Craniofacial Cartilage Gene Expression in Developing Zebrafish – Xiong K.M., Mehta V., Peterson R.E. and Heideman W. The Toxicologist (a Supplement to Toxicological Sciences) 96 (1) Abstract #1015, p 210.
- 2006 - 7th International Conference on Zebrafish Development and Genetics. Madison, WI. Structural and Functional Defects in Cardiac Valve Formation in Embryonic Zebrafish Exposed to 2,3,7,8-Terachlorodibenzo-p-Dioxin. Mehta V, Peterson R.E. and Heideman W –Abstract #448.
- 2005 - Society Of Toxicology. 2005 Meeting - New Orleans, LA Identification of Zebrafish ARNT1 Homologs: TCDD Developmental Toxicity in Zebrafish Requires ARNT1– Prasch A.L., Tanguay R.L., Mehta V, Heideman W and Peterson R.E.
- 2004 - 6th International Conference on Zebrafish Development and Genetics. Madison, WI.
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